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Updated: Apr 11, 2026

A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues
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A Method for Measuring RNA N6-methyladenosine Modifications in Cells and Tissues

Published on: December 5, 2016

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N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency.

Xiao Wang1, Boxuan Simen Zhao1, Ian A Roundtree2

  • 1Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA; Howard Hughes Medical Institute, The University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA.

Cell
|June 6, 2015
PubMed
Summary

N(6)-methyladenosine (m(6)A) in mRNA controls gene expression. Reader proteins YTHDF1 and YTHDF2 regulate mRNA stability and protein synthesis, enabling rapid and controlled cellular responses.

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