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Registers of multiple sclerosis in Denmark.

N Koch-Henriksen1,2, M Magyari2,3, B Laursen4

  • 1Department of Clinical Epidemiology, University of Aarhus, Aarhus, Denmark.

Acta Neurologica Scandinavica
|June 6, 2015
PubMed
Summary

Denmark has two national multiple sclerosis (MS) registers: the Danish Multiple Sclerosis Registry (DMSR) for incidence and prevalence, and the Danish Multiple Sclerosis Treatment Register for treatment outcomes. Both provide valuable epidemiological data.

Keywords:
epidemiologyincidencematchingmultiple sclerosisnational registrypersonal Idprevalence

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Area of Science:

  • Epidemiology
  • Neurology
  • Public Health

Background:

  • Denmark maintains two comprehensive nationwide population-based registers for multiple sclerosis (MS).
  • The Danish Multiple Sclerosis Registry (DMSR) focuses on epidemiological data, including prevalence, incidence, and survival.
  • The Danish Multiple Sclerosis Treatment Register monitors patients receiving disease-modifying treatments since 1996.

Purpose of the Study:

  • To describe the scope and utility of Denmark's two national MS registers.
  • To highlight their contributions to understanding MS risk factors and treatment efficacy.
  • To inform researchers about available data for epidemiological and clinical studies.

Main Methods:

  • Utilizing data from the Danish Multiple Sclerosis Registry (DMSR) for historical prospective studies on environmental exposures.
  • Analyzing data from the Danish Multiple Sclerosis Treatment Register for treatment-related outcomes, including antibody development.
  • Leveraging nationwide population-based data for comprehensive epidemiological analysis.

Main Results:

  • The DMSR has provided nationwide incidence and prevalence data for multiple sclerosis.
  • Studies using the DMSR have identified and exonerated suspected environmental risk factors for MS.
  • The Treatment Register has advanced knowledge regarding antibodies against biological drugs used in MS therapy.

Conclusions:

  • Denmark's dual MS registers offer robust resources for epidemiological research and clinical insights.
  • These registers are crucial for identifying MS risk factors and evaluating treatment effectiveness.
  • Continued use of these registers will enhance understanding and management of multiple sclerosis.