Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Glaucoma: Overview01:25

Glaucoma: Overview

1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.7K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.7K
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

245
Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
245

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A physics-informed neural network framework for plant-wide prediction and dynamic control of wastewater treatment.

Bioresource technology·2026
Same author

Research progress on the application of manganese oxides in constructed wetlands: Efficiency, mechanisms, and prospects.

Bioresource technology·2026
Same author

Treatment performance and mechanism of source-separated blackwater using an earthworm-based reactor for rural applications.

Journal of environmental management·2026
Same author

Development of a Layer-by-Layer Zein/CMCS Microcapsule Platform for Bacteriophage Delivery: A Proof-of-Concept Study Using a Model Phage in Sea Bass.

Foods (Basel, Switzerland)·2026
Same author

Konjac glucomannan-based edible coatings for preservation of Dendrobium officinale.

International journal of biological macromolecules·2025
Same author

Development of polylactic acid aluminized film/cellulosic paper composite paper-based material for herba houttuyniae preservation.

International journal of biological macromolecules·2025

Related Experiment Video

Updated: Apr 11, 2026

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
04:59

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation

Published on: July 7, 2023

3.3K

Toric Intraocular Lens Outcomes in Patients With Glaucoma.

Reay H Brown, Le Zhong, Caroline W Bozeman

    Journal of Refractive Surgery (Thorofare, N.J. : 1995)
    |June 6, 2015
    PubMed
    Summary

    Toric intraocular lenses effectively reduced astigmatism and improved vision in patients with glaucoma and corneal astigmatism. This surgery also led to a decrease in intraocular pressure, enhancing visual outcomes.

    More Related Videos

    Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
    10:10

    Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

    Published on: February 15, 2022

    2.0K
    Ultrasound Cyclo Plasty in Eyes with Glaucoma
    05:05

    Ultrasound Cyclo Plasty in Eyes with Glaucoma

    Published on: January 26, 2018

    12.8K

    Related Experiment Videos

    Last Updated: Apr 11, 2026

    Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
    04:59

    Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation

    Published on: July 7, 2023

    3.3K
    Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
    10:10

    Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

    Published on: February 15, 2022

    2.0K
    Ultrasound Cyclo Plasty in Eyes with Glaucoma
    05:05

    Ultrasound Cyclo Plasty in Eyes with Glaucoma

    Published on: January 26, 2018

    12.8K

    Area of Science:

    • Ophthalmology
    • Corneal Surgery
    • Glaucoma Management

    Background:

    • Glaucoma and corneal astigmatism present unique challenges in cataract surgery.
    • Toric intraocular lenses (IOLs) are designed to correct astigmatism during cataract surgery.

    Purpose of the Study:

    • To evaluate the outcomes of toric IOL implantation in patients with co-existing glaucoma and corneal astigmatism.
    • To assess the impact on visual acuity, refractive error, and intraocular pressure.

    Main Methods:

    • Retrospective case series of 126 eyes from 87 patients undergoing cataract surgery with AcrySof toric IOLs.
    • Preoperative and postoperative measurements included corrected distance visual acuity (CDVA), intraocular pressure (IOP), and refractive astigmatism.
    • Postoperative measurements also included uncorrected distance visual acuity (UDVA) and toric alignment.

    Main Results:

    • Significant reduction in refractive astigmatism from 1.47 D preoperatively to 0.31 D postoperatively.
    • High percentage of eyes achieved excellent UDVA (98% 20/40 or better, 47% 20/20).
    • Mean IOP decreased by 2.3 mm Hg, and mean toric misalignment was 4.4°.

    Conclusions:

    • Toric IOL implantation is a reliable method for reducing astigmatism in patients with glaucoma and cataract.
    • The procedure effectively improves uncorrected vision and can contribute to IOP reduction.