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Updated: Apr 11, 2026

Phenotypic Analysis and Isolation of Murine Hematopoietic Stem Cells and Lineage-committed Progenitors
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Published on: July 8, 2012

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Bringing Blood Stem Cell Phenotype, Genotype, and Function Closer Together

Wenlian Qiao1, Peter W Zandstra1

  • 1The Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON M5S 3E1, Canada; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.

Cell Stem Cell
|June 6, 2015
PubMed

Imperfect purity, subtypes, and retrospective functional assays compromise efforts to define the molecular identity of hematopoietic stem cells (HSCs). In this issue of Cell Stem Cell, Wilson et al. (2015) use a single-cell-based bioinformatics-experimental strategy to extract a consensus molecular signature from heterogeneous HSC pools. Their data and strategy provide a powerful resource for stem cell characterization.

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