Related Experiment Video
Updated: Apr 11, 2026
06:51
A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
5.9K
[Congenital hemangiomas: Report on ten patients]
Summary
Congenital hemangiomas (CHs) are rare vascular tumors. This study highlights their varied presentation, potential overlap with vascular malformations, and that rapidly involuting CHs often leave sequelae.
Area of Science:
- Dermatology
- Pediatrics
- Vascular Surgery
Context:
- Congenital hemangiomas (CHs) are rare congenital vascular tumors.
- Limited literature exists on their clinical presentation and progression.
- This study investigates CHs diagnosed and treated at Besançon Hospital from 2008 to 2014.
Purpose:
- To describe the clinical presentation, diagnosis, and treatment of congenital hemangiomas.
- To analyze the progression and outcomes of different types of CHs, including rapidly involuting CHs (RICH) and non-involuting CHs (NICH).
- To explore potential overlapping features between CHs and vascular malformations.
Summary:
- Ten CHs (seven RICH, three NICH) in male infants were analyzed.
- Diagnosis was primarily clinical, with RICH showing variable involution times and sequelae (lipoatrophy, dysplastic veins).
- NICH presented without complications, but overlapping forms between RICH and NICH, and CH and vascular malformations were observed.
Impact:
- This study confirms the rarity of CHs and reports novel findings on NICH location and sex ratio.
- It underscores the polymorphous clinical presentation and progression of CHs.
- Findings suggest a potential link between proliferation and malformation phenomena in the origin of these lesions.
