[Treatment of vulvar intra-epithelial neoplasias with Imiquimod]

J Paternotte1, T Hebert1, L Ouldamer2

  • 1Service de gynécologie-obstétrique et médecine fœtale, université François-Rabelais, CHRU de Tours, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.

The incidence of vulvar intra-epithelial neoplasia (VIN) is increasing in the developed countries especially in young women. There is little consensus regarding the optimal management. Surgery used to be the gold standard. Alternatives to surgery are now needed for the treatment of VIN. Many studies investigated the effectiveness of Imiquimod 5% cream in this pathology. We present a literature review of the results published on the subject.

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