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Rupture of massive coronary artery aneurysm resulting in cardiac tamponade
Takeshi Kondo1, Motonori Takahashi1, Kanako Nakagawa1
1Division of Legal Medicine, Department of Community Medicine and Social Health Science, Kobe University Graduate School of Medicine, Kobe, Japan.
Insights
A massive coronary artery aneurysm ruptured, causing cardiac tamponade and death in a middle-aged man. This rare case highlights the severe consequences of atherosclerotic coronary artery aneurysms.
Area of Science:
- Cardiology
- Pathology
Background:
- Coronary artery aneurysms are rare dilatations exceeding 1.5 times normal artery width.
- Rupture of these aneurysms can lead to life-threatening complications.
Purpose of the Study:
- To report a fatal case of a ruptured massive coronary artery aneurysm.
- To describe the pathological findings and cause of death.
Main Methods:
- Autopsy and histological examination of a deceased middle-aged male.
- Analysis of pericardial blood, coronary arteries, aorta, and heart.
Main Results:
- Two true aneurysms of the right coronary artery were identified; one ruptured, causing 270mL hemopericardium.
- Severe atherosclerosis was noted in the coronary arteries and aorta.
- The cause of death was cardiac tamponade due to the ruptured atherosclerotic aneurysm.
Conclusions:
- Rupture of giant coronary atherosclerotic aneurysms can be rapidly fatal.
- Atherosclerosis is a key underlying pathology in these aneurysms.
- This case underscores the importance of recognizing and managing coronary artery aneurysms.
Abstract:
Coronary artery aneurysm is a fairly uncommon clinical entity, which is defined by a characteristic dilatation that exceeds 1.5 times the width of normal adjacent coronary artery segments. In the present report, we describe a case of rupture of a massive coronary artery aneurysm. A man in his 40s was found dead in his bed. The pericardial cavity contained 270mL of blood with 428.2g of coagulation. Two true aneurysms of the right coronary artery were identified. A proximal aneurysm, adjacent to the right auricle, had ruptured on the right. A distal unruptured aneurysm was identified 5.1cm distal to the proximal ruptured aneurysm. Atherosclerosis of the coronary arteries and aorta was severe. The heart weighed 799.1g and showed concentric ventricular hypertrophy, myocardial thinning, and patchy fibrosis. Histological analysis showed that both aneurysms were purely atherosclerotic true aneurysms without considerable inflammation. The cause of death was determined as cardiac tamponade due to rupture of a giant coronary atherosclerotic aneurysm.
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