Schmorl Nodes Mimicking Osteolytic Bone Metastases
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Updated: Apr 11, 2026

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
Naoya Niwa1, Toru Nishiyama1, Choichiro Ozu1
1Department of Urology, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Abstract:
Bone is the third most common site of metastasis from upper tract urothelial carcinoma after radical nephroureterectomy. Although bone biopsy is the gold standard for the diagnosis of bone metastases, they can usually be diagnosed on the basis of imaging tests. We describe a case of upper tract urothelial carcinoma after radical nephroureterectomy presenting with a Schmorl node in the third lumbar vertebra, mimicking lytic bone metastasis. Differentiation of bone metastases from Schmorl nodes is essential for the appropriate management of patients with malignancy.
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