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Structure of 1-amidino-3-(3-sulfamoylphenyl)urea hydrochloride

P A Sutton1, V Cody

  • 1Medical Foundation of Buffalo, NY 14203.

Acta Crystallographica. Section C, Crystal Structure Communications
|May 15, 1989
PubMed

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Direct alkylation is not a suitable method for synthesizing amines because it produces polyalkylated products. Gabriel synthesis is the most preferred method to exclusively make primary amines. The method uses phthalimide, which contains a protected form of nitrogen that participates in alkylation only once to predominantly give primary amines.
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