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Updated: Apr 11, 2026
05:09
Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
Published on: April 28, 2023
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Urethroplasty in radiation-induced strictures
Jaclyn C Milose1, Christopher M Gonzalez
1Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Current Opinion in Urology
|June 8, 2015
Summary
Urethroplasty is a feasible treatment for radiation-induced urethral strictures, offering durable outcomes. Patients should be counseled on potential urinary incontinence risks following the procedure.
Area of Science:
- Urology
- Reconstructive Surgery
Background:
- Urethral stricture disease often requires urethroplasty for definitive treatment.
- The efficacy of urethroplasty in radiation-induced strictures was previously uncertain.
Purpose of the Study:
- To review the feasibility and outcomes of urethroplasty in patients with urethral stricture secondary to pelvic radiation exposure.
- To assess the success rates and potential complications of this surgical approach.
Main Methods:
- Review of recent studies on urethroplasty for radiation-induced urethral strictures.
- Analysis of stricture characteristics, surgical techniques, and patient outcomes.
Main Results:
- Urethroplasty for radiation-induced strictures is technically challenging but yields acceptable success rates.
- Most radiation strictures are short, bulbomembranous, and suitable for excision and primary anastomosis.
- Higher rates of postoperative urinary incontinence are observed, but erectile function is generally preserved.
Conclusions:
- Urethroplasty is a viable option for men with radiation-induced urethral strictures.
- Informed consent regarding the risk of urinary incontinence is crucial for these patients.
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