Related Experiment Video
Updated: Apr 11, 2026

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
Published on: December 1, 2023
Reprint of: Relationship between cataract severity and socioeconomic status
Jason D Wesolosky1, Christopher J Rudnisky2
1Department of Ophthalmology, University of Alberta, Edmonton, Alta.
Objective:
To determine the relationship between cataract severity and socioeconomic status (SES).
Design:
Retrospective, observational case series. A total of 1350 eyes underwent phacoemulsification cataract extraction by a single surgeon using an Alcon Infiniti system. Cataract severity was measured using phaco time in seconds. SES was measured using area-level aggregate census data: median income, education, proportion of common-law couples, and employment rate. Preoperative best corrected visual acuity was obtained and converted to logarithm of the minimum angle of resolution values. For patients undergoing bilateral surgery, the generalized estimating equation was used to account for the correlation between eyes. Univariate analyses were performed using simple regression, and multivariate analyses were performed to account for variables with significant relationships (p < 0.05) on univariate testing. Sensitivity analyses were performed to assess the effect of including patient age in the controlled analyses.
Results:
Multivariate analyses demonstrated that cataracts were more severe when the median income was lower (p = 0.001) and the proportion of common-law couples living in a patient's community (p = 0.012) and the unemployment rate (p = 0.002) were higher. These associations persisted even when controlling for patient age.
Conclusion:
Patients of lower SES have more severe cataracts.
Related Concept Videos
Photoreceptors and Visual Pathways
Close Relationships and Culture
Glaucoma: Overview
Criteria for Causality: Bradford Hill Criteria - I

