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Updated: Apr 11, 2026

Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds
Published on: October 29, 2015
Pestiviruses: old enemies and new challenges
Julia F Ridpath1, John D Neill1
1Ruminant Diseases and Immunology Research Unit,National Animal Disease Center,ARS/USDA,Ames,IA,USA.
Pestiviruses, including Bovine viral diarrhea virus (BVDV), present global challenges. International collaboration is crucial for controlling emerging pestiviruses and understanding their impact on animal health.
Area of Science:
- Veterinary Virology
- Infectious Diseases
- Animal Health
Background:
- A joint meeting by the US BVDV Symposia Committee and the European Society for Veterinary Virology highlighted the need for global pestivirus control.
- The meeting theme, "Pestiviruses: Old enemies and new challenges," addressed the inadequacy of regional disease control strategies.
- The global trade in animal products necessitates a unified approach to managing pestivirus infections.
Discussion:
- Emerging pestiviruses, like HoBi-like viruses, require international cooperation for effective management.
- Papers in this issue cover pestiviruses' interaction with the immune system, their genetic variability, and the emergence of new strains.
- Pestivirus control programs are discussed in the context of a global challenge.
Key Insights:
- Regional pestivirus control efforts are insufficient due to international animal product trade.
- Collaborative, global strategies are essential for controlling newly identified pestiviruses.
- Understanding pestivirus genetic diversity and host immune responses is key to developing effective control measures.
Outlook:
- Future research should focus on international collaboration for pestivirus surveillance and control.
- Continued investigation into the evolution and spread of pestiviruses is critical for preventing future outbreaks.
- The development of unified global strategies for pestivirus management will enhance animal health worldwide.
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