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Updated: Apr 11, 2026

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
Published on: August 24, 2012
Disruption of reconsolidation processes is a balancing act - can it really account for change in psychotherapy?
Rainer Spanagel1, Martin Bohus2
1Institute of Psychopharmacology,Central Institute of Mental Health,Faculty of Medicine Mannheim,Heidelberg University,J5,D-68159 Mannheim,Germany.rainer.spanagel@zi-mannheim.de.
Abstract:
Lane et al. argue that any psychotherapeutic intervention at its core acts on reactivated memories via the process of reconsolidation which leads to modified memory traces. From our perspective, this model (1) only explains a small subsegment of psychotherapeutic mechanisms and (2) ignores the difficulties of generating reliable experimental conditions that allow interference with reconsolidation processes and - if successful - their transient nature.
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