Related Experiment Video
Updated: Apr 11, 2026

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum
Published on: February 15, 2015
'Activity-silent' working memory in prefrontal cortex: a dynamic coding framework
1Oxford Centre for Human Brain Activity, University of Oxford, Oxford, UK.
Abstract:
Working memory (WM) provides the functional backbone to high-level cognition. Maintenance in WM is often assumed to depend on the stationary persistence of neural activity patterns that represent memory content. However, accumulating evidence suggests that persistent delay activity does not always accompany WM maintenance but instead seems to wax and wane as a function of the current task relevance of memoranda. Furthermore, new methods for measuring and analysing population-level patterns show that activity states are highly dynamic. At first glance, these dynamics seem at odds with the very nature of WM. How can we keep a stable thought in mind while brain activity is constantly changing? This review considers how neural dynamics might be functionally important for WM maintenance.
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