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Published on: January 28, 2020
[Evolution of cardiovascular risk factors in patients undergoing percutaneous coronary intervention]
Jael Voces-Álvarez1, Gabriel J Díaz-Grávalos2
1Escuela Universitaria de Enfermería de Ourense, Universidad de Vigo, Ourense, España.
Insights
Controlling cardiovascular risk factors after percutaneous coronary intervention (PCI) is crucial. While blood pressure and cholesterol improved six months post-PCI, many patients still had uncontrolled risk factors, with age and chronic kidney disease linked to new events.
Area of Science:
- Cardiology
- Interventional Cardiology
- Public Health
Background:
- Cardiovascular risk factors (CVRF) significantly impact outcomes following percutaneous coronary intervention (PCI) for ischemic heart disease.
- Effective management of CVRF is essential for improving patient prognosis after PCI.
Purpose of the Study:
- To evaluate the changes in CVRF six months after PCI.
- To determine the association between CVRF and the occurrence of new cardiovascular events post-PCI.
Main Methods:
- A descriptive case series study analyzed data from 222 patients.
- Key variables included age, sex, chronic kidney disease (CKD), cholesterol, blood pressure, smoking status, and BMI, measured before and 6 months after PCI.
- Logistic regression was used to identify predictors of new events (death or repeat PCI).
Main Results:
- The study included 222 patients (75.2% male, mean age 70.2 years).
- Prevalence of hypertension, hyperlipidemia, smoking, and diabetes was high (57.7%, 55.9%, 50.4%, 28.2% respectively).
- Six months post-PCI, blood pressure and total cholesterol decreased, but 33% had uncontrolled CVRF. New events occurred in 5% (death) and 15.3% (new PCI). Age (OR 1.06) and CKD (OR 3.7) were associated with new events.
Conclusions:
- A high prevalence of CVRF exists in patients undergoing PCI.
- While some CVRF like blood pressure and cholesterol showed improvement, overall control remained incomplete at six months.
- New cardiovascular events were observed in a significant proportion of patients, with advanced age and CKD identified as key risk factors.
Aim:
Controlling cardiovascular risk factors (CVRF) is important for the outcome of interventional practices (percutaneous coronary intervention [PCI]) in ischemic heart disease. The aim is to determine the evolution of the CVRF 6 months after the intervention and their relationship with new events.
Method:
A descriptive study was conducted on a case series. The variables recorded were: age, sex and chronic kidney disease (CKD), as well as total (TC) and HDL cholesterol, systolic (SBP) and diastolic blood pressure (DBP), smoking habit, and body mass index (BMI), before PCI and after 6 months. The occurrence of death or new PCI during the follow-up was considered an independent variable in a logistic regression analysis. A P<.05 was assumed significant.
Results:
A total of 222 cases (75.2% males) were included, with a mean age of 70.2 (SD 11.9) years, of whom 57.7% were hypertensive patients, 55.9% had hyperlipidemia, 50.4% were smokers or ex-smokers, and 28.2% were diabetics. After 6 months, 5% died, and 15.3% needed a new PCI, while 33% of the sample had all the CVRF considered. Decreases were observed in SBP (-3.3 mmHg), DBP (-2.6 mmHg), and TC (-35.2mg/dl). The emergence of new event was associated with age (OR: 1.06; P=.003) and CKD (OR: 3.7; P=.04).
Conclusions:
There is a high prevalence of CVRF. After 6 months, there was a decrease in blood pressure and TC, although incomplete control of CVRF was found. One fifth of the patients had an event in that period, showing association with age and CKD.
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