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Microfluidics in Assessing Platelet Function
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Prasugrel Hydrochloride.

Mahmoud M H Al Omari1, Nidal A Qinna2, Iyad S Rashid1

  • 1The Jordanian Pharmaceutical Manufacturing Co., Naor, Jordan.

Profiles of Drug Substances, Excipients, and Related Methodology
|June 9, 2015
PubMed
Summary
This summary is machine-generated.

This review details prasugrel hydrochloride (HCl), a crucial antiplatelet medication. It covers synthesis, properties, and applications, offering a comprehensive resource for researchers and clinicians.

Keywords:
ADMEAnalysisAntiplatelet agentComprehensive profilePrasugrelPreparationStabilityThienopyridine

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Area of Science:

  • Pharmacology and Medicinal Chemistry
  • Chemical Synthesis and Analysis

Background:

  • Prasugrel hydrochloride (HCl) is a significant antiplatelet agent used in cardiovascular medicine.
  • Existing literature provides fragmented information on its comprehensive profile.

Purpose of the Study:

  • To compile a detailed profile of prasugrel HCl.
  • To consolidate information on its chemical properties, synthesis, and applications.

Main Methods:

  • Literature review encompassing 158 references.
  • Compilation of data on nomenclature, formulae, elemental analysis, and physical properties.
  • Discussion of preparation methods, analytical techniques, stability, and pharmacology.

Main Results:

  • A comprehensive description of prasugrel HCl, including its chemical and physical characteristics.
  • Detailed methods for the preparation of prasugrel HCl, its intermediates, and derivatives.
  • An overview of analytical methods, stability, applications, and pharmacological actions.

Conclusions:

  • This profile serves as a centralized resource for prasugrel HCl.
  • It provides essential information for researchers, formulators, and clinicians working with prasugrel HCl.