Report: Analysis on pathogen distribution and drug-resistance of incision infection caused by vascular operation

Area of Science:

• Infectious Diseases
• Surgical Site Infections
• Antimicrobial Resistance

Background:

• Postoperative incision infections are a significant concern following vascular operations.
• Understanding pathogen distribution and antimicrobial susceptibility is crucial for effective treatment and prevention.

Purpose of the Study:

• To investigate the distribution of pathogens causing incision infections after vascular surgery.
• To determine the drug resistance patterns of these pathogens.
• To identify strategies for reducing postoperative incision infection rates.

Main Methods:

• Retrospective analysis of 635 patients undergoing vascular operations between January 2008 and December 2012.
• Statistical analysis of infection rates, pathogen types, and antimicrobial susceptibility.
• Identification of isolated pathogens using standard laboratory methods.

Main Results:

• An overall incision infection rate of 2.52% (16 out of 635 patients) was observed.
• A total of 27 bacterial strains were isolated, with Gram-positive bacteria (62.96%) more prevalent than Gram-negative bacteria (37.04%).
• All isolated bacteria exhibited high resistance to common antibacterial drugs, except for imipenem, to which they showed sensitivity.

Conclusions:

• Postoperative incision infections following vascular surgery are associated with significant antimicrobial resistance.
• Effective reduction of surgical site infections can be achieved through pre-operative complication management, appropriate post-operative antibiotic use, strict aseptic techniques during surgery, and thorough wound irrigation.
• Imipenem shows potential as an effective treatment option against the identified pathogens.