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Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model
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Chagas Heart Disease: An Update

Lindsey H Malik1, Gagan D Singh1, Ezra A Amsterdam1

  • 1Division of Cardiovascular Medicine, Department of Internal Medicine, University of California (Davis) Medical Center, Sacramento.

The American Journal of Medicine
|June 9, 2015
PubMed

Insights

Chagas disease (American trypanosomiasis) caused by Trypanosoma cruzi is spreading globally due to migration. Limited medical awareness is increasing its public health concern in the US.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Parasitology

Background:

  • Chagas disease, caused by Trypanosoma cruzi, is a significant cause of cardiac disease globally.
  • Historically endemic to South and Central America, Chagas disease is now spreading worldwide due to population migration.
  • An estimated 6-7 million people are infected globally, with a notable increase in the US.

Purpose of the Study:

  • To highlight the growing public health concern of Chagas disease in the US.
  • To underscore the impact of migration on the global spread of American trypanosomiasis.
  • To address the limited awareness of Chagas disease within the medical community.

Main Methods:

  • Analysis of migration patterns of individuals from Trypanosoma cruzi-endemic countries.
  • Review of epidemiological data on Chagas disease prevalence.
  • Assessment of medical community awareness regarding American trypanosomiasis.

Main Results:

  • The US has seen a surge in Chagas disease cases due to immigration.
  • Preliminary estimates place the US seventh in the Western Hemisphere for Trypanosoma cruzi infections.
  • Lack of medical awareness poses a significant public health challenge.

Conclusions:

  • Chagas disease is an emerging public health issue in the US, driven by migration.
  • Increased awareness and diagnostic capabilities are crucial for managing the growing number of cases.
  • The global distribution of Trypanosoma cruzi necessitates a broader public health approach.

Keywords:
ChagasHeart disease

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