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Use of ciprofloxacin during breastfeeding

Yusuf Cem Kaplan, Gideon Koren

    Canadian Family Physician Medecin De Famille Canadien
    |June 9, 2015
    PubMed

    Insights

    Breastfeeding mothers can safely take ciprofloxacin for urinary tract infections. Low drug levels in breast milk mean osteoarticular toxicity risk to infants is minimal, so stopping breastfeeding is unnecessary.

    Area of Science:

    • Pharmacology
    • Pediatrics
    • Infectious Diseases

    Background:

    • Urinary tract infections (UTIs) are common in women of childbearing age.
    • Ciprofloxacin is a frequently prescribed antibiotic for UTIs.
    • Concerns exist regarding potential adverse effects of ciprofloxacin in breastfed infants, specifically osteoarticular toxicity.

    Observation:

    • A clinical question arose regarding the safety of prescribing ciprofloxacin to a breastfeeding mother.
    • The specific concern was the potential risk of osteoarticular toxicity in a 9-week-old infant.
    • The patient's clinical scenario involved a UTI requiring antibiotic treatment.

    Findings:

    • Ciprofloxacin levels excreted in breast milk are generally low.
    • Studies indicate no significant increase in osteoarticular toxicity in neonates and children receiving systemic ciprofloxacin.
    • Existing data suggests minimal risk to the infant from ciprofloxacin exposure via breast milk.

    Implications:

    • Breastfeeding interruption is likely unnecessary when mothers are treated with ciprofloxacin for UTIs.
    • This finding supports the continuation of breastfeeding during maternal antibiotic therapy.
    • Further research could explore long-term outcomes, but current evidence favors maintaining breastfeeding.
    Abstract

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