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Updated: Apr 11, 2026

Multimodal Optical Imaging Platform for Studying Cellular Metabolism

Multimodal Optical Imaging Platform for Studying Cellular Metabolism

Published on: June 6, 2025

Image-guided surgery using multimodality strategy and molecular probes.

Lei Xi¹, Hubei Jiang^1,2

¹School of Physical Electronics, University of Electronic Science and Technology of China, Chengdu, China.

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology

|June 9, 2015

Summary

This summary is machine-generated.

Image-guided surgery uses advanced imaging and molecular probes to improve cancer resection. A multimodal strategy with specific probes offers an optimal approach for better patient outcomes.

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Dual-modality Molecular Cartography: Integrating Multiplex mRNA Detection with Protein Imaging Mass Cytometry

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Area of Science:

Oncology
Surgical Innovation
Medical Imaging

Background:

Maximizing tumor excision while preserving healthy tissue is crucial for cancer surgery.
Current methods struggle with precise tumor margin identification and detecting residual disease.
Advanced imaging and molecular probes are being explored to enhance surgical precision.

Purpose of the Study:

To review current imaging techniques and molecular probes for image-guided surgery.
To highlight progress in multimodal image-guided surgery using specific molecular navigation.
To discuss optimal strategies for image-guided surgery across all patient care stages.

Main Methods:

Review of typical imaging techniques and molecular probes.
Focused review of multimodal image-guided surgery advancements.
Discussion of preoperative, intraoperative, and postoperative strategies.

Main Results:

Combining imaging techniques with molecular probes shows promise for image-guided surgery.
Multimodality strategies and specific molecular probes address limitations of individual techniques.
Optimal strategies encompass preoperative scanning, intraoperative inspection, and postoperative care.

Conclusions:

Multimodal image-guided surgery with specific molecular probes represents an optimal approach.
This strategy aims to improve tumor resection completeness and patient survival rates.
Comprehensive planning from preoperative to postoperative care is essential for successful image-guided surgery.