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Management and treatment of chronic urticaria (CU)

M Maurer1, M K Church1, M Gonçalo2

  • 1Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité - Universitatsmedizin Berlin, Berlin, Germany.

Journal of the European Academy of Dermatology and Venereology : JEADV
|June 9, 2015
PubMed

Developments increasing our understanding of chronic urticaria have resulted in the simplification and improvement of available treatments. Currently, many treatments target mast cell mediators, but we can now disrupt mast cell activation with the anti-IgE antibody omalizumab, which has markedly advanced the treatment landscape for patients with difficult-to-treat urticaria. Current guidelines provide a framework for the management and treatment of patients with CU but, as each patient is different, knowledge and experience of specialist dermatologists and allergists are key to effective pharmacotherapy. This article reviews the different therapeutic options for patients with chronic spontaneous urticaria (also called chronic idiopathic urticaria) or chronic inducible urticaria and discusses management of special populations or special circumstances related to CU.

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