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SPECT Myocardial Blood Flow Quantitation Concludes Equivocal Myocardial Perfusion SPECT Studies to Increase
Lung-Ching Chen1, Chih-Yuan Lin, Ing-Jou Chen
1From the *Division of Cardiology, Shin Kong Wu-Ho Su Memorial Hospital, Taipei, Taiwan; †School of Medicine, National Yang-Ming University, Taipei, Taiwan; ‡Department of Medical Physics Research, Bailing Cloud Biomedical Technologies Innovation, Taipei, Taiwan; §Department of Nuclear Medicine, Shin Kong Wu-Ho Su Memorial Hospital, Taipei, Taiwan; ∥School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan; and ¶Nuclear Science and Engineering Institute, University of Missouri-Columbia, Columbia, Missouri.
Insights
Dynamic SPECT/CT myocardial blood flow quantitation aids coronary artery disease detection. This technique offers valuable clinical applications for diagnosis and management, especially where PET tracers are unavailable.
Area of Science:
- Cardiovascular Imaging
- Nuclear Medicine
- Radiology
Background:
- Myocardial blood flow (MBF) quantitation using dynamic SPECT/CT is emerging as a valuable tool.
- It offers an alternative for coronary artery disease (CAD) diagnosis in regions lacking myocardial perfusion PET tracers.
- This technique enhances the detection and assessment of CAD.
Abstract:
Recently, myocardial blood flow quantitation with dynamic SPECT/CT has been reported to enhance the detection of coronary artery disease in human. This advance has created important clinical applications to coronary artery disease diagnosis and management for areas where myocardial perfusion PET tracers are not available. We present 2 clinical cases that undergone a combined test of 1-day rest/dipyridamole-stress dynamic SPECT and ECG-gated myocardial perfusion SPECT scans using an integrated imaging protocol and demonstrate that flow parameters are capable to conclude equivocal myocardial perfusion SPECT studies, therefore increasing diagnostic benefits to add value in making clinical decisions.
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