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Updated: Apr 11, 2026
Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
Published on: November 10, 2017
Core-Shell Upconversion Nanoparticle@Metal-Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted
Yantao Li1, Jinglong Tang1, Liangcan He1
1Key Laboratory of Nanosystem and Hierarchical Fabrication, Chinese Academy of Sciences, National Center for Nanoscience and Technology, No. 11, Beiyitiao, Zhongguancun, Beijing, 100190, P. R. China.
Abstract:
Core-shell upconversion nanoparticle@metal-organic framework (UCNP@MOF) nanostructures are constructed by coating hexagonal NaYF4 :Yb,Er nanoparticle (NP) cores with amino-functionalized iron carboxylate MOF shells. These nanostructures combine the near-infrared optical property of the UCNP cores and the T2 -magnetic response (MR) imaging property of the MOF shells. After surface modification, the core-shell nanostructures are demonstrated as high-resolution nanoprobes for targeted luminescence/MR imaging both in vitro and in vivo.
