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[Metastatic collision tumour. A case report].

Oscar Zenón Rosas-Guerra1, Jorge Alfonso Pérez-Castro y Vázquez1, Gumaro Hugolino Andrade-López1

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Summary

Collision tumors, rare growths with two distinct origins in one organ, present diagnostic and treatment challenges. This case highlights a unique instance of bilateral ovarian adenocarcinoma and Mullerian tumor, emphasizing the need for further research.

Keywords:
CarcinomaCollision tumourTumor de colisiónTumor mixed mesodermicTumor mixto mesodérmico

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Area of Science:

  • Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Collision tumors are exceptionally rare, defined by the coexistence of two distinct histological tumor types within the same organ.
  • While the exact incidence is unknown, their rarity poses significant diagnostic and therapeutic challenges.

Observation:

  • A 71-year-old female presented with symptoms of intestinal obstruction due to a right flank abdominal mass.
  • Histopathological examination revealed bilateral ovarian adenocarcinoma and a metastatic collision tumor comprising well-differentiated adenocarcinoma and a mixed malignant mesodermic Mullerian tumor.

Findings:

  • The patient's collision tumor involved two distinct histological types: adenocarcinoma and a mixed malignant mesodermic Mullerian tumor.
  • Despite surgical debulking and adjuvant chemotherapy, the patient experienced a poor outcome, with mortality within 24 months.

Implications:

  • This case underscores the extreme rarity of collision tumors and the lack of established statistical data or specific treatment protocols.
  • Accurate histopathological diagnosis is crucial for identifying these complex tumors.
  • The poor response to conventional treatment highlights the need for novel therapeutic strategies for such rare oncological entities.