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Related Experiment Video

Updated: Apr 11, 2026

Long Term Intravital Multiphoton Microscopy Imaging of Immune Cells in Healthy and Diseased Liver Using CXCR6.Gfp Reporter Mice

Long Term Intravital Multiphoton Microscopy Imaging of Immune Cells in Healthy and Diseased Liver Using CXCR6.Gfp Reporter Mice

Published on: March 24, 2015

Understanding liver immunology using intravital microscopy.

Pedro Elias Marques¹, André Gustavo Oliveira¹, Lynne Chang²

¹Laboratório de Imunobiofotônica, Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Brazil.

Journal of Hepatology

|June 10, 2015

Summary

This review highlights the liver

Keywords:

In vivo imaging Liver immunology Liver infection Liver intravital microscopy Sterile injury

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Last Updated: Apr 11, 2026

Long Term Intravital Multiphoton Microscopy Imaging of Immune Cells in Healthy and Diseased Liver Using CXCR6.Gfp Reporter Mice

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Intravital Microscopy Imaging of the Liver following Leishmania Infection: An Assessment of Hepatic Hemodynamics

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Published on: July 28, 2015

Area of Science:

Immunology
Hepatology
Microscopy

Background:

The liver's role has expanded beyond metabolism to encompass immune system regulation.
Intravital microscopy has revealed the liver as a critical site for immune responses.

Purpose of the Study:

To review advances in liver immunology.
To highlight the role of intravital microscopy in understanding liver immune responses.

Main Methods:

Literature review focusing on intravital microscopy.
Analysis of studies on liver immunology in disease models.

Main Results:

The liver orchestrates innate and adaptive immunity through specialized cell populations.
Intravital microscopy visualizes leukocyte recruitment, pathogen clearance, and mediator production in the liver.
Advances in imaging reveal hepatic immune responses in ischemia/reperfusion, acute liver injury, and infections.

Conclusions:

The liver is a dynamic immunological organ.
Intravital microscopy is crucial for dissecting liver immune mechanisms.
Understanding liver immunology is key for treating liver diseases.