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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
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Prostate Cancer Registries: Current Status and Future Directions.
Giorgio Gandaglia1, Freddie Bray2, Matthew R Cooperberg3
1Unit of Urology/Department of Oncology, San Raffaele Hospital, Milan, Italy.
European Urology
|June 10, 2015
Summary
Prostate cancer registries offer valuable data for research, aiding in understanding disease progression and treatment outcomes. Careful consideration of their strengths and limitations is crucial for advancing prostate cancer care.
Area of Science:
- Oncology
- Epidemiology
- Health Services Research
Background:
- Disease-specific registries are vital for prostate cancer (PCa) research.
- These registries enroll a significant number of patients, providing crucial data.
Purpose of the Study:
- To evaluate existing prostate cancer registries.
- To describe their strengths and limitations.
- To discuss their future role in outcomes research.
Main Methods:
- A literature review was conducted using Medline, Embase, and Web of Science databases.
- Search terms included "prostate cancer," "outcomes," and "registries."
- Studies published between January 2005 and January 2015 were included.
Main Results:
- Multiple population-based and prospective disease-specific registries for prostate cancer are available.
- These registries provide data on incidence, mortality, risk factors, treatment disparities, quality of care, and outcomes.
- Statistical methods can address data limitations and enhance analysis validity.
Conclusions:
- Prostate cancer registries offer clinically relevant information for patient management.
- While randomized controlled trials are the gold standard, registries play an increasingly important role in PCa research.
- Future improvements in data quality and collection will enhance registry relevance.
Keywords:
Disease-specific outcomesEpidemiologyPopulation-basedProspective registriesProstate cancerStatistical approachesMore Related Videos
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