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Deep brain stimulation to reduce sexual drive.

Johannes Fuss1, Matthias K Auer1, Sarah V Biedermann1

  • 1From the Institute for Sex Research and Forensic Psychiatry, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Germany (Fuss, Briken); the RG Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany (Auer); the Department of Psychiatry and Psychotherapy, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Germany (Biedermann); and the Department of Neurology, University of Heidelberg, Germany (Hacke).

Journal of Psychiatry & Neuroscience : JPN
|June 10, 2015
PubMed
Summary

Deep brain stimulation (DBS) may offer an alternative to reduce high sexual drive in paraphilic patients, potentially avoiding the side effects of current pharmacological therapies.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Medical Ethics

Background:

  • Limited treatment options exist for reducing high sexual drive in paraphilic patients at risk for sexual offending.
  • Current pharmacological therapies lower testosterone, causing severe systemic side effects.

Purpose of the Study:

  • To explore deep brain stimulation (DBS) as a potential treatment to reduce high sexual drive.
  • To investigate DBS as an alternative to pharmacological interventions for paraphilic disorders.

Main Methods:

  • Discusses DBS as a treatment strategy for severe paraphilic disorders.
  • References historical stereotactic interventions targeting the ventromedial hypothalamus in the 1970s.

Main Results:

  • Hypothesizes that DBS of sexual drive circuits could reduce sexual urges.
  • Suggests DBS could avoid systemic side effects associated with antiandrogenic drugs.

Conclusions:

  • DBS presents a potential novel therapeutic approach for paraphilic disorders.
  • Significant ethical and practical challenges must be addressed before considering DBS for paraphilic patients.