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Ménage a Trois to Form the Tricellular Junction
David Flores-Benitez1, Elisabeth Knust1
1Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307-Dresden, Germany.
Developmental Cell
|June 10, 2015
Abstract:
Tricellular junctions tightly seal epithelia at the corners of three cells. In this issue of Developmental Cell, Byri et al. (2015) show that Anakonda, a novel Drosophila transmembrane protein, contains an unusual tripartite extracellular domain organization, which explains the tripartite septum filling the tricellular junction, previously revealed by ultrastructure analysis.