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Idiotypic network in myasthenia gravis
1Department of Medicine, Karolinska Hospital, Stockholm, Sweden.
Clinical and Experimental Rheumatology
|September 1, 1989
Abstract:
Fluctuations in idiotypic and anti-idiotypic Ab levels over time in two myasthenia gravis patients were found to vary either inversely with one another or in relation to one another. A pair of 46-year-old female twins in which one of the twins developed myasthenia gravis while the other remained healthy were also studied. Ab specificities and immunoglobulin specificities available in the B cell repertoire were found to be similar in both twins.