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Related Experiment Videos

QUAD: a computer package for the analysis of QUantal Assay Data.

B J Morgan1, S E Pack, D M Smith

  • 1Institute of Mathematics, University of Kent, Canterbury, U.K.

Computer Methods and Programs in Biomedicine
|December 1, 1989
PubMed
Summary

The QUAD computer package offers advanced logit analysis for quantal assay data. It provides flexible data analysis, diagnostics, and extended models with graphical displays for microcomputers.

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Area of Science:

  • Biostatistics
  • Computational Biology
  • Toxicology

Background:

  • Quantal assay data analysis requires specialized statistical methods.
  • Existing software may lack flexibility or advanced modeling capabilities.
  • Microcomputer accessibility for statistical analysis is increasing.

Purpose of the Study:

  • To introduce the QUAD computer package for quantal assay data analysis.
  • To detail the functionalities including logit analysis, dose transformations, and model diagnostics.
  • To showcase the integration of statistical research and microcomputer graphics.

Main Methods:

  • Development of a menu-driven package named QUAD using Advanced BASIC.
  • Implementation of logit analysis for quantal response data.

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  • Inclusion of dose transformations, alternative confidence intervals, and model diagnostics.
  • Main Results:

    • QUAD performs logit analysis and provides flexible data analysis options.
    • The package offers diagnostics for assessing model fit.
    • Two families of extended models, including logit as a special case, are provided and fitted.

    Conclusions:

    • QUAD is a user-friendly, menu-driven package for microcomputers.
    • It incorporates advanced statistical research for robust data analysis.
    • Further developments are planned for this pilot package.