Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bulimia Nervosa01:30

Bulimia Nervosa

1.1K
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
1.1K
Frequency-dependent Selection01:21

Frequency-dependent Selection

24.5K
When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.
24.5K
Anorexia Nervosa01:28

Anorexia Nervosa

2.0K
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
2.0K
Conservation of Small Populations02:04

Conservation of Small Populations

17.7K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
17.7K
Human Genetics01:28

Human Genetics

1.9K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
1.9K
Pedigree Analysis01:35

Pedigree Analysis

91.3K
Overview
91.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Laboratory maintenance does not alter ecological and physiological patterns among species: a Drosophila case study.

Journal of evolutionary biology·2018
Same author

Evolution of sociality in spiders leads to depleted genomic diversity at both population and species levels.

Molecular ecology·2017
Same author

GENETIC VARIATION IN TIME AND SPACE: MICROSATELLITE ANALYSIS OF EXTINCT AND EXTANT POPULATIONS OF ATLANTIC SALMON.

Evolution; international journal of organic evolution·2017
Same author

Few genetic and environmental correlations between life history and stress resistance traits affect adaptation to fluctuating thermal regimes.

Heredity·2016
Same author

Patterns of longevity and fecundity at two temperatures in a set of heat-selected recombinant inbred lines of Drosophila melanogaster.

Biogerontology·2015
Same author

Phenotypic plasticity is not affected by experimental evolution in constant, predictable or unpredictable fluctuating thermal environments.

Journal of evolutionary biology·2015

Related Experiment Video

Updated: Apr 11, 2026

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
07:30

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

25.8K

Inbreeding depression across a nutritional stress continuum.

M F Schou1, V Loeschcke1, T N Kristensen2

  • 1Department of Bioscience, Aarhus University, Aarhus, Denmark.

Heredity
|June 11, 2015
PubMed
Summary
This summary is machine-generated.

Inbreeding and environmental stress interact, worsening fitness reduction in populations. This study shows inbreeding depression intensifies with greater nutritional stress, especially in smaller populations.

More Related Videos

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay
06:45

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay

Published on: July 26, 2017

7.2K
Protocol for Assessing the Relative Effects of Environment and Genetics on Antler and Body Growth for a Long-lived Cervid
09:09

Protocol for Assessing the Relative Effects of Environment and Genetics on Antler and Body Growth for a Long-lived Cervid

Published on: August 8, 2017

8.1K

Related Experiment Videos

Last Updated: Apr 11, 2026

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
07:30

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

25.8K
A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay
06:45

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay

Published on: July 26, 2017

7.2K
Protocol for Assessing the Relative Effects of Environment and Genetics on Antler and Body Growth for a Long-lived Cervid
09:09

Protocol for Assessing the Relative Effects of Environment and Genetics on Antler and Body Growth for a Long-lived Cervid

Published on: August 8, 2017

8.1K

Area of Science:

  • Evolutionary biology
  • Population genetics
  • Ecology

Background:

  • Natural populations face inbreeding and genetic drift due to factors like nonrandom mating or small population size.
  • Environmental challenges can interact with increased homozygosity, leading to synergistic fitness declines.
  • Previous studies on inbreeding-environment interactions often used limited stress levels, restricting detailed analysis.

Purpose of the Study:

  • To investigate the synergistic effects of inbreeding and nutritional stress on fitness in Drosophila melanogaster.
  • To quantify the impact of varying population sizes on inbreeding depression under different nutritional conditions.
  • To elucidate the relationship between inbreeding depression and nutritional stress gradients.

Main Methods:

  • Established replicate Drosophila melanogaster populations at three sizes (10, 50, 500) for 25 generations.
  • Imposed a nutritional stress gradient using 11 yeast concentrations in developmental media.
  • Assessed egg-to-adult viability and adult body mass to measure fitness consequences.

Main Results:

  • Confirmed significant inbreeding-environment interactions affecting viability and body mass, with depression worsening under higher stress.
  • Observed a steeper increase in inbreeding depression with nutritional stress in smaller populations (size 10) compared to larger ones (size 50).
  • Identified a nonlinear relationship between inbreeding depression and nutritional stress, and a faster accumulation of lethal equivalents in smaller populations.

Conclusions:

  • Inbreeding depression is exacerbated by higher nutritional stress levels.
  • Smaller population sizes amplify the negative fitness consequences of inbreeding-environment interactions.
  • The study provides strong evidence for pronounced deleterious effects of inbreeding-environment interactions under increased stress and inbreeding.