Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Parathyroid Glands

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...

Hormones and Bone Tissue

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...

Pharmacokinetics in Pediatric Patients: Drug Metabolism

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...

Skeleton and Calcium Homeostasis

Skeleton and Calcium Homeostasis

Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...

Synthesis and Functions of Calcitonin

Synthesis and Functions of Calcitonin

Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Future Directions and Innovations in Mineralocorticoid Receptor Antagonist Therapy.

The Journal of the Association of Physicians of India·2026

Same author

Does cognitive behavioural therapy have an impact on insomnia and salivary cortisol level during perimenopause?

Psychiatria Danubina·2026

Same author

Comparative Evaluation of Bioresorbable Membrane with and without Hyaluronic Acid in the Treatment of Intra-Bony Defects - A Clinical and Radiographic Study.

Journal of pharmacy & bioallied sciences·2026

Same author

Opt Deep CSSAN: Optimized Deep Convolutional Spectral-Spatial Attention Network for hyperspectral image classification.

Computational biology and chemistry·2025

Same author

Determining the efficacy of phytoconstituents of <i>Ficus religiosa</i> L. against dermatophytes through invitro and insilico approaches.

In silico pharmacology·2025

Same author

Surface modification of polycaprolactone with sulfated alginate for enhanced binding of a heparin-binding protein.

Journal of materials chemistry. B·2025

Same journal

Hypothyroidism Related Kidney Disease - A Report of Two Cases.

Indian journal of nephrology·2025

Same journal

A Unique Case of Joubert Syndrome with Concurrent IgA Nephropathy and Nephronophthisis in an Adult Patient.

Indian journal of nephrology·2025

Same journal

Severe Rhabdomyolysis Due to Presumed Drug Interactions of Dapagliflozin with Rosuvastatin: A Case Report.

Indian journal of nephrology·2025

Same journal

Urinary Neutrophil Gelatinase Associated Lipocalin as a Marker of Nephropathy in Type 2 Diabetic Patients.

Indian journal of nephrology·2025

Same journal

Prevalence of Human Leukocyte Antigen Alleles Polymorphism in North Indian Population.

Indian journal of nephrology·2025

Same journal

The Imaging Gamut of Von-Hippel-Lindau.

Indian journal of nephrology·2025

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 11, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

Primary hyperparathyroidism in a child.

A Anitha¹, K Babu², V Siddini²

¹Department of Nephrology, Manipal Hospital, Salem, Tamil Nadu, India.

Indian Journal of Nephrology

|June 11, 2015

Summary

This summary is machine-generated.

Primary hyperparathyroidism, a rare childhood condition, can cause kidney stones and muscle weakness. A 12-year-old girl with these symptoms was successfully treated with parathyroid adenoma removal.

Area of Science:

Pediatric Endocrinology
Surgical Oncology
Nephrology

Background:

Primary hyperparathyroidism is uncommon in pediatric populations.
Clinical manifestations in children can include nephrolithiasis and neuromuscular symptoms.

Keywords:

Parathyroid adenoma primary hyperparathyroidism recurrent renal calculi

More Related Videos

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

Published on: March 14, 2017

Related Experiment Videos

Last Updated: Apr 11, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

Published on: March 14, 2017