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Mehmet Fethi Ceylan1, Savas Guner1, Levent Ediz2
1Orthopedics and Traumatology.
Insights
Elevated Red blood cell distribution width (RDW) levels are linked to atrial fibrillation (AF) in hypertensive patients. Increased RDW may signal AF presence or development in those with hypertension.
Area of Science:
- Cardiology
- Hematology
- Internal Medicine
Background:
- Atrial fibrillation (AF) is a common arrhythmia increasing stroke and mortality risk.
- Hypertension is a significant risk factor for developing atrial fibrillation.
- Elevated Red blood cell distribution width (RDW) is observed in various cardiovascular conditions.
Purpose of the Study:
- To investigate the association between Red blood cell distribution width (RDW) and atrial fibrillation (AF) in hypertensive individuals.
Main Methods:
- Retrospective analysis of 126 hypertensive patients.
- Comparison between 63 hypertensive patients with AF and 63 without AF, matched for age and sex.
- Logistic regression and ROC curve analysis to identify risk factors and cut-off points.
Main Results:
- RDW levels were significantly higher in hypertensive patients with AF (15.13±1.58) compared to those without AF (14.05±1.15).
- RDW and left atrial dimension were identified as independent risk factors for AF (RDW Odds Ratio: 1.846).
- The determined cut-off point for RDW was 14.195, with 71.4% sensitivity and 56% specificity.
Conclusions:
- Hypertensive patients with atrial fibrillation exhibit higher Red blood cell distribution width (RDW) levels.
- An elevated RDW in hypertensive patients may serve as an early indicator for the presence or development of atrial fibrillation.
Background:
A trial fibrillation (AF) is the most common cardiac arrhythmia and increases the risk of stroke and death. Patients with hypertensive have an increased risk of developing atrial fibrillation. RDW (Red blood cell distribution width) levels are elevated in cardiovascular disorders including heart failure, stable coronary disease, acute coronary syndrome, slow coronary flow and stroke.
Objective:
To investigate the relation between RDW and AF in patients with hypertensive.
Method:
We retrospectively examined 126 consecutive hypertensive patients (63 hypertensive patients with AF and 63 hypertensive patients without AF matched with age and sex.
Results:
The mean age of the study population was 71,09± 8,50 (af group) and 70,97±8,24 (non-af group) years. RDW level was different among patients with atrial fibrillation and without atrial fibrillation.(15,13±1,58 and 14,05±1,15 p<001). Logistic regression analysis showed that RDW and left atrial dimension were only independently risk factory associated with atrial fibrillation. (Rdw odds ratio:1,846 CI; 1,221-2,793 p<0,05). Roc curve analyses were applied to determine the cut-off point. Cut-off point was at 14,195 and Sensitive, specificity was %71,4, %56 respectively.
Conclusion:
RDW levels were higher in hypertensive patients with atrial fibrillation. An increased RDW level in the patient with hypertension may alert physician on developing or presence of atrial fibrillation.
