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Updated: Apr 11, 2026
A Coregistered Ultrasound and Photoacoustic Imaging Protocol for the Transvaginal Imaging of Ovarian Lesions
Published on: March 3, 2023
Complementary Role of Ultrasound in Management of Gestational Trophoblastic Disease
Mahrooz Malek1, Behnaz Moradi1, Azam Sadat Mousavi2
1Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Background:
Transvaginal Ultrasonography is a noninvasive and inexpensive medical imaging tool used for the diagnosis of various diseases.
Objectives:
To identify an effective method to identify high-risk patients for developing malignancy after molar evacuation.
Patients And Methods:
A prospective serial assessment of 19 patients with gestational trophoblastic disease was performed. Clinical and laboratory data, transvaginal ultrasound and Doppler findings were evaluated the day before evacuation. They were followed-up in the first week after evacuation and every two weeks during the next two months, then every month until the sixth month.
Results:
Ovarian theca lutein cysts (P = 0.018) (among pre-evacuation factors) and first week ultrasound (P = 0.02) can help in detecting high-risk patients. Even though, when β-hCG titer is not available in a high-risk patient, post evacuation myometrial involvement (P = 0.005) is a useful sign for detecting persistency.
Conclusions:
Some ultrasonographic features of molar pregnancy have capability to predict malignancy in the course of disease.
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