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Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children
07:36

Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children

Published on: September 1, 2018

Photo-evoked eyelid microvibration in newborn infants and children--reflex arc and maturational change

A Yasuhara, A Hori, Y Kobayashi

    Electromyography and Clinical Neurophysiology
    |November 1, 1989
    PubMed

    Insights

    Photo-evoked eyelid microvibration (PEMV) latency shortens with age due to nerve myelination. This study establishes age-related normal values for PEMV, crucial for understanding neurological development and diagnosing related conditions.

    Area of Science:

    • Neuroscience
    • Developmental Biology
    • Ophthalmology

    Background:

    • Photo-evoked eyelid microvibration (PEMV) is a reflex observed in humans.
    • The maturational process of PEMV and its underlying neural pathway are not fully understood.
    • Understanding PEMV development is important for assessing neurological function in infants and children.

    Purpose of the Study:

    • To investigate the maturational process of photo-evoked eyelid microvibration (PEMV) in newborns, children, and adults.
    • To establish age-related normal values for PEMV latency.
    • To explore the influence of specific neurological conditions and treatments on PEMV.

    Main Methods:

    • Studied 166 newborns, 72 children, and 10 adults.
    • Measured the latency of photo-evoked eyelid microvibration (PEMV).
    • Analyzed age-related changes and evaluated effects of specific conditions.

    Main Results:

    • PEMV latency significantly shortens with age, correlating with nerve fiber myelination.
    • Established age-related normal values for PEMV latency.
    • Observed alterations in PEMV due to retinoblastoma, facial nerve paralysis, holoprosencephaly, and muscle relaxants.

    Conclusions:

    • Nerve myelination is a key factor in the maturation of the PEMV reflex pathway.
    • The study provides normative data for PEMV, aiding in the diagnosis of developmental and neurological disorders.
    • PEMV is a sensitive indicator of the integrity of the visual-oculomotor pathway.

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