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Long-term care and management of Wilson's disease in the GDR
H Bachmann1, J Lössner, H J Kühn
1Clinic of Neurology, Karl Marx University, Leipzig, GDR.
European Neurology
|January 1, 1989
Abstract:
Diagnosis, long-term management and family investigations of Wilson's disease are provided by selected clinical institutions in the GDR. From 187 patients detected since 1949, 111 are alive. In spite of the principal effectiveness of penicillamine treatment, confirmed by the disappearance of most of the central nervous system symptoms and successful professional rehabilitation of many patients, insufficient therapeutic discipline, psychosocial disturbances and penicillamine side-effects forcing its substitution by zinc or triethylenetetramine dihydrochloride in 14 cases need our further attention.