Related Experiment Videos
Effect of retinyl acetate on nuclear proteins in rabbit liver
J Pałyga1, K Grochała, A Kowalski
1Department of Genetics, Educational University of Kielce, Poland.
General Pharmacology
|January 1, 1989
Abstract:
1. Retinyl acetate injected intraperitoneally to adult rabbits fed on standard diet caused detectable changes in the polyacrylamide gel patterns of liver nucleoplasmic and 0.35 M NaCl-soluble chromatin proteins. 2. Both histones and non-histone proteins soluble in 5 M urea were not affected in vitamin A-treated animals. 3. It seems that variations in liver nuclear proteins from retinyl acetate-administered rabbits may reflect retinol-dependent alterations in structure and function of their chromatins.