Microfilariae recurrence in graded murrah buffalo treated with repeated doses of ivermectin

Filariosis is one of the common parasitic diseases of animals and man caused by a small group of filarid nematodes throughout the world. This disease is highly prevalent in hot and humid arenas of India especially hilly parts of Tarai region of Uttar Pradesh and coastal areas of Andhra Pradesh, (Kumar et al. 2005). Microfilariosis is manifested by pyerxia, loss of appetite, reduced milk yield, weakness, edema of dependent parts. Macrofilaricidal and micerfilaricidal are the most effective drugs to get rid of the larvae and adult worm burden. Ivermectin 200 μg/kg body wt subcutaneous route is used as a curative drug in present clinical case and animal was responded well with the treatment. After 2 months the animal brought with same symptoms which were reported earlier. Wet blood film examination revealed recurrence of microfilariae in the peripheral blood circulation.