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Preoperative CRP levels is not predictive early renal dysfunction after coronary artery bypass surgery

Veysel Sahin1, Mehmet Besir Akpinar1, Erol Sevim2

  • 1Division of Cardiac Surgery, Sifa University Medical Faculty Izmir, Turkey.

International Journal of Clinical and Experimental Medicine
|June 12, 2015
PubMed

Insights

This study found no significant correlation between preoperative C-reactive protein (CRP) levels and early kidney dysfunction following cardiac surgery. Preoperative CRP levels did not predict postoperative renal function in patients undergoing cardiac operations.

Area of Science:

  • Cardiology
  • Nephrology
  • Biochemistry

Background:

  • Assessing preoperative C-reactive protein (CRP) levels is crucial for understanding potential complications after cardiac surgery.
  • Early renal dysfunction is a significant concern in patients undergoing cardiac operations.

Purpose of the Study:

  • To investigate the relationship between preoperative C-reactive protein (CRP) levels and the incidence of early renal dysfunction after cardiac surgery.

Main Methods:

  • A retrospective analysis of 546 patients undergoing cardiac operations between January 2012 and December 2013.
  • Patients were categorized into two groups based on preoperative CRP levels: normal (<0.5 mg/dL) and high (≥0.5 mg/dL).
  • Comparison of preoperative and postoperative renal function markers (serum BUN, creatinine, and CrCl) between the two groups.

Main Results:

  • Significant differences in median preoperative and postoperative CRP levels were observed between the high and normal CRP groups.
  • No significant differences were found in preoperative or postoperative levels of serum blood urea nitrogen (BUN), creatinine, or creatinine clearance (CrCl) between the groups.
  • Early postoperative renal function indicators did not differ significantly between patients with normal and high preoperative CRP levels.

Conclusions:

  • Early renal function, assessed by creatinine and creatinine clearance, is not significantly different between patients with normal and high preoperative CRP levels.
  • Preoperative CRP levels do not appear to be correlated with early renal function after coronary artery bypass grafting (CABG) surgery.
Abstract

Keywords:
C-reactive proteincardiopulmonary bypassrenal function

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