Does Self-Efficacy Affect Cognitive Performance in Persons with Clinically Isolated Syndrome and Early Relapsing...

Area of Science:

• Neuroscience
• Psychology

Background:

• Lowered self-efficacy negatively impacts physical activities in multiple sclerosis (MS).
• The relationship between self-efficacy and cognitive performance in early MS stages requires further investigation.

Purpose of the Study:

• To examine the association between self-efficacy and cognitive performance in individuals with Clinically Isolated Syndrome (CIS) and early Relapsing-Remitting MS (eRRMS).

Main Methods:

• Thirty-three CIS and eRRMS patients were assessed for self-efficacy (MSSES-18), cognition (CDR System), fatigue (MFIS-5), depressive symptoms (BDI), disease impact (MSIS-29), and disability (EDSS).
• Correlative and stepwise regression analyses were employed to determine relationships and predictors.

Main Results:

• Total self-efficacy showed significant correlations with Power of Attention (r=0.65), Reaction Time Variability (r=0.57), and Speed of Memory (r=0.53).
• Self-efficacy predicted substantial variability in cognitive functions, accounting for up to 40% of Power of Attention and Speed of Memory.
• Disease impact was a significant predictor of self-efficacy, explaining 65% of total self-efficacy variability.

Conclusions:

• Self-efficacy may positively influence cognitive performance in individuals with CIS and early MS.
• Preserving self-efficacy through disease activity prevention is crucial for cognitive health in early MS stages.