Visceral Kaposi's Sarcoma Presenting as Upper Gastrointestinal Bleeding

Area of Science:

• Oncology
• Gastroenterology
• Infectious Diseases

Background:

• Highly active antiretroviral therapy (HAART) has significantly reduced acquired immunodeficiency syndrome (AIDS)-related Kaposi's sarcoma (KS) incidence.
• Cutaneous Kaposi's sarcoma is common, but gastrointestinal (GI) involvement is less recognized yet critical.
• GI-KS poses severe risks, including perforation, obstruction, and bleeding.

Purpose of the Study:

• To report a rare case of GI-KS presenting with upper GI bleeding.
• To emphasize the importance of considering GI-KS in HIV-infected individuals with gastrointestinal symptoms.

Main Methods:

• Case report of a human immunodeficiency virus (HIV)-infected transgender individual.
• Clinical presentation of upper gastrointestinal bleeding.

Main Results:

• The patient presented with upper GI bleeding, a rare manifestation of GI-KS.
• This case underscores the potential severity and varied presentations of GI-KS.

Conclusions:

• Prompt diagnosis and early treatment are crucial for managing GI-KS.
• Awareness of GI-KS is essential for effective patient care in the context of HIV infection.