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Updated: Apr 10, 2026
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Published on: November 17, 2020
Localized Relapse of Primary Plasma Cell Leukaemia in the Central Nervous System
Christian W Eskelund1, Niels Frost Andersen1
1Department of Haematology, Aarhus University Hospital, Aarhus, Denmark.
Abstract:
Primary plasma cell leukaemia (pPCL) is a rare and aggressive form of plasma cell malignancies with a very poor prognosis. Compared to other plasma cell malignancies the tendency to extramedullary spread is increased; however central nervous system (CNS) involvement is rare and only reported in few cases. We report the case of a 61-year-old man who was diagnosed with pPCL and achieved a complete remission after autologous stem cell transplantation but had a relapse in the CNS without systemic disease.
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