Infected Baerveldt Glaucoma Drainage Device by Aspergillus niger

Nurul-Laila Salim1, Yaakub Azhany1, Zaidah Abdul Rahman2

  • 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia ; Hospital Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

Insights

Fungal endophthalmitis after glaucoma surgery is rare and difficult to treat. This case highlights successful treatment of Aspergillus endophthalmitis using intravitreal and topical voriconazole.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Surgical Complications

Background:

  • Fungal endophthalmitis is a rare but serious complication following glaucoma drainage device surgery.
  • Subtle initial symptoms and treatment resistance contribute to poor visual prognosis.
  • Intravitreal voriconazole has less documented experience compared to Amphotericin B for fungal endophthalmitis.

Purpose of the Study:

  • To report a successful management strategy for Aspergillus endophthalmitis post-glaucoma drainage device implantation.
  • To evaluate the efficacy of intravitreal and topical voriconazole in a challenging clinical scenario.

Main Methods:

  • A case presentation of a patient who developed Aspergillus endophthalmitis after Baerveldt glaucoma drainage device implantation.
  • Treatment involved a combination of intravitreal and topical voriconazole administration.

Main Results:

  • Successful resolution of Aspergillus endophthalmitis was achieved with the prescribed treatment regimen.
  • The patient's visual outcome, while not explicitly detailed, was positive under this management approach.

Conclusions:

  • Intravitreal and topical voriconazole represent a viable and effective treatment option for fungal endophthalmitis, including Aspergillus species, following glaucoma surgery.
  • This approach may be considered in cases where traditional treatments are less effective or experienced.