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Updated: Apr 10, 2026

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
Published on: October 5, 2018
Experimentally Induced Mammalian Models of Glaucoma
Makoto Ishikawa1, Takeshi Yoshitomi1, Charles F Zorumski2
1Department of Ophthalmology, Akita Graduate University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
Abstract:
A wide variety of animal models have been used to study glaucoma. Although these models provide valuable information about the disease, there is still no ideal model for studying glaucoma due to its complex pathogenesis. Animal models for glaucoma are pivotal for clarifying glaucoma etiology and for developing novel therapeutic strategies to halt disease progression. In this review paper, we summarize some of the major findings obtained in various glaucoma models and examine the strengths and limitations of these models.

