Acute Coronary Syndrome In HIV Naïve Patient With Low CD4 Count And No Other Significant Risk Factors: Case Report...

Area of Science:

• Cardiology
• Infectious Diseases
• Public Health

Background:

• Coronary artery disease (CAD) is a significant concern in Human Immunodeficiency Virus (HIV)-infected individuals.
• HIV patients face a higher mortality rate due to CAD compared to the general population.

Purpose of the Study:

• To investigate the characteristics and prevalence of coronary artery disease (CAD) in patients with Human Immunodeficiency Virus (HIV).
• To understand the typical presentation and coronary anatomy in HIV-infected individuals experiencing acute coronary syndrome (ACS).

Main Methods:

• Review of clinical data from HIV-infected patients presenting with acute coronary syndrome (ACS).
• Analysis of patient demographics, clinical presentation, and coronary angiography findings.
• Comparison of coronary artery disease prevalence with non-HIV controls.

Main Results:

• The typical patient is a male in his mid-to-late 40s presenting with acute myocardial infarction (MI), often with ST-segment elevation.
• Coronary anatomy findings are variable, with some studies indicating a higher prevalence of single-vessel disease and others showing increased multi-vessel disease in HIV patients compared to controls.
• Acute coronary syndrome (ACS) is the most common manifestation of CAD in this population.

Conclusions:

• Coronary artery disease (CAD) represents a leading cause of mortality in Human Immunodeficiency Virus (HIV) patients.
• Early recognition and management of ACS are crucial in HIV-infected individuals.
• Further research is needed to elucidate the specific mechanisms driving CAD in HIV and optimize treatment strategies.