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Updated: Apr 10, 2026

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
Published on: September 4, 2017
A new Bayesian model applied to cytogenetic partial body irradiation estimation
Manuel Higueras1, Pedro Puig2, Elizabeth A Ainsbury3
1Public Health England Centre for Radiation, Chemical and Environmental Hazards, Chilton, Didcot, Oxon OX11 0RQ, UK Departament de Matemàtiques, Universitat Autònoma de Barcelona, Barcelona, Spain manuel.higueras-hernaez@phe.gov.uk.
Abstract:
A new zero-inflated Poisson model is introduced for the estimation of partial body irradiation dose and fraction of body irradiated. The Bayes factors are introduced as tools to help determine whether a data set of chromosomal aberrations obtained from a blood sample reflects partial or whole body irradiation. Two examples of simulated cytogenetic radiation exposure data are presented to demonstrate the usefulness of this methodology in cytogenetic biological dosimetry.
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