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Peyronie's Disease: AUA Guideline
Ajay Nehra1, Ralph Alterowitz1, Daniel J Culkin1
1American Urological Association Education and Research, Inc., Linthicum, Maryland.
The Journal of Urology
|June 13, 2015
Summary
This guideline offers a clinical framework for diagnosing and treating Peyronie
Area of Science:
- Urology
- Andrology
- Medical Guidelines
Background:
- Peyronie's disease (PD) affects penile health and requires clear diagnostic and treatment protocols.
- Existing literature on PD management is continually expanding, necessitating updated clinical strategies.
Purpose of the Study:
- To establish a comprehensive clinical framework for the diagnosis and treatment of Peyronie's disease.
- To synthesize current evidence into actionable guideline statements for clinicians.
Main Methods:
- A systematic literature review was conducted across PubMed, EMBASE, and Cochrane databases (1965-2015).
- Inclusion/exclusion criteria were applied to 303 relevant peer-reviewed articles.
- Evidence quality was rated (A, B, C), informing treatment recommendation strength.
Main Results:
- Guideline statements were developed based on the systematic review's evidence base.
- Treatment recommendations range from Strong to Conditional, based on evidence quality and risk-benefit analysis.
- Consensus statements for diagnosis were formulated due to limited published evidence.
Conclusions:
- The guideline provides a flexible clinical strategy for Peyronie's disease, not rigid rules.
- Individualized patient care, considering history and goals, is paramount.
- The strategy will be updated as scientific understanding and treatments for PD evolve.
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