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Updated: Apr 10, 2026

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
The Impact of Trying Electronic Cigarettes on Cigarette Smoking by College Students: A Prospective Analysis
Erin L Sutfin1, Beth A Reboussin1, Beata Debinski1
1Erin L. Sutfin, Beata Debinski, Kimberly G. Wagoner, and Mark Wolfson are with the Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC. Beth A. Reboussin is with the Department of Biostatistical Sciences, Wake Forest School of Medicine. John Spangler is with the Department of Family and Community Medicine, Wake Forest School of Medicine.
Objectives:
We assessed the impact of trying electronic cigarettes (e-cigarettes) on future cigarette smoking in a sample of smokers enrolled in college.
Methods:
In this longitudinal study, first-semester college students at 7 colleges in North Carolina and 4 in Virginia completed a baseline survey and 5 follow-up surveys between fall 2010 and fall 2013. Current cigarette smoking at wave 6 was the primary outcome. Participants (n = 271) reported current cigarette smoking at baseline and no history of e-cigarette use. We measured trying e-cigarettes at each wave, defined as use in the past 6 months.
Results:
By wave 5, 43.5% had tried e-cigarettes. Even after controlling for other variables associated with cigarette smoking, trying e-cigarettes was a significant predictor of cigarette smoking at wave 6 (adjusted odds ratio [AOR] = 2.48; 95% confidence interval [CI] = 1.32, 4.66), as were friends' cigarette smoking (AOR = 4.20; 95% CI = 2.22, 7.96) and lifetime use of other tobacco products (AOR = 1.63; 95% CI = 1.22, 2.17).
Conclusions:
Trying e-cigarettes during college did not deter cigarette smoking and may have contributed to continued smoking.
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