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A step toward simplified detection of serum albumin on SDS-PAGE using an environment-sensitive flavone sensor
Bin Liu1, Yi Pang, Rachida Bouhenni
1Department of Chemistry, University of Akron, Akron, Ohio 44325, USA. yp5@uakron.edu.
Abstract:
In this study, we report a series of novel flavone-based sensors that exhibit a superior fluorescence response when interacting with serum albumin in real serum samples and in acrylamide gels. The detection limit of probe 4 for serum albumin solution is 0.09 μg mL(-1), and the detectable volume for monkey serum reaches as low as 0.03 μL.

