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Is cholic acid responsible for embryo-toxicity of the post-receptive uterine environment?
A Psychoyos1, D Roche, A Gravanis
1Laboratoire de Physiologie de la Reproduction, CNRS UA 549, Hôpital de Bicêtre, Bâtiment INSERM, Le Kremlin-Bicêtre, France.
Human Reproduction (Oxford, England)
|October 1, 1989
Abstract:
HPLC analysis of the embryo-toxic fraction of human uterine fluid, collected between the 22nd and 25th days of the menstrual cycle, revealed the presence of cholic acid at high concentrations. It is suggested that cholic acid could be responsible for the embryo-toxicity of the uterine environment, which follows the receptive period for implantation.